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Irys Extract.

Rani Arielly¹, Yuval Ebenstein¹

¹School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Center for Nanoscience and Nanotechnology, Tel Aviv University, Tel Aviv 69978, Israel.

Bioinformatics (Oxford, England)

|October 17, 2017

Summary

This summary is machine-generated.

Irys Extract software provides easy access to genomic data from the BioNano Genomics Irys platform. This tool generates aligned intensity profiles compatible with genome browsers, simplifying genomic analysis.

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Area of Science:

Genomics
Bioinformatics
Software Development

Background:

The BioNano Genomics Irys platform generates large datasets requiring specialized tools for analysis.
Accessing and interpreting raw genomic data can be challenging for researchers.

Purpose of the Study:

To develop a software tool, Irys Extract, for efficient processing of BioNano Genomics Irys data.
To provide users with accessible raw data formats and genetically aligned intensity profiles.
To ensure compatibility with standard genomic visualization tools.

Main Methods:

Developed using Matlab R2015a.
Tested with IrysView 2.4.0.15879 and AutoDetect 2.1.4.9159.
Designed for Microsoft Windows operating systems (7-10).

Main Results:

Irys Extract facilitates easy access to cropped images and aligned intensity profiles.
Intensity profiles are converted to BED format for compatibility with genome browsers like UCSC Genome Browser.
The software simplifies the generation of genomic information from Irys platform data.

Conclusions:

Irys Extract is a valuable tool for researchers using the BioNano Genomics Irys platform.
The software enhances data accessibility and usability for genomic analysis.
It promotes seamless integration with existing bioinformatics workflows and visualization tools.