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Keratitis After Post-Kala-Azar Dermal Leishmaniasis.
Aditya Pradhan1, Samar Basak, Tuhin Chowdhury
1Department of Cornea and External Disease, Disha Eye Hospitals Pvt Ltd, Barrackpore, Kolkata, India.
Cornea
|October 18, 2017
Summary
This study reports two cases of keratitis, an eye inflammation, following post-kala-azar dermal leishmaniasis (PKDL). Topical corticosteroids effectively treated the condition, leading to improved vision.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Dermatology
Background:
- Post-kala-azar dermal leishmaniasis (PKDL) is a chronic skin manifestation of leishmaniasis.
- Ocular complications of leishmaniasis are rare, especially in immunocompetent individuals.
Observation:
- Two immunocompetent male patients with PKDL developed keratitis.
- Clinical presentation included dense stromal infiltrates in the cornea.
- Microbiological investigations were negative for causative organisms.
Findings:
- Both patients were treated with oral miltefosine for PKDL.
- Topical corticosteroid therapy (prednisolone) under antibiotic cover resulted in dramatic improvement.
- Complete resolution of corneal infiltrates and good visual outcomes were achieved.
Implications:
- This is the first report of keratitis occurring after PKDL in immunocompetent patients.
- Awareness of this potential ocular manifestation of leishmaniasis is crucial for clinicians.
- Topical corticosteroids may be an effective treatment for PKDL-associated keratitis.