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Updated: Feb 20, 2026

Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria
Published on: May 25, 2022
Bacterial vaginosis
Phillip Hay1,2
1Wandsworth Integrated Sexual Health, Courtyard Clinic, St. George's Hospital, Blackshaw Road, London, SW17 0QT, UK.
Abstract:
Bacterial vaginosis is the most prevalent cause of abnormal vaginal discharge in women of childbearing age. It can have a major impact on quality of life and psychological wellbeing if frequently recurrent and strongly symptomatic. The use of molecular techniques to study the vaginal microbiome is increasing our understanding of the dynamic changes in flora that occur in health and disease. It might soon be possible to separate Gardnerella into different pathogenic and non-pathogenic species. Many groups are studying compounds that can disrupt the biofilm which is dominated by Gardnerella and Atopobium vaginae. Several studies in the last decade support the concept of bacterial vaginosis as a sexually transmitted infection.
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