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Hepatic morphology abnormalities: beyond cirrhosis.

Giuseppe Mamone1, Kelvin Cortis2, Aquilina Sarah2

  • 1Radiology Unit, Diagnostic and Therapeutic Services, IRCCS ISMETT (Mediterranean Institute for Transplantation and Advanced Specialized Therapies), via Tricomi 5, 90127, Palermo, Italy. gmamone@ismett.edu.

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PubMed
Summary

Radiologists can diagnose cirrhosis by recognizing hepatic morphological changes on CT and MRI scans. This review details conditions that mimic cirrhosis, aiding in accurate differential diagnosis.

Keywords:
CirrhosisComputed tomographyLiverMagnetic resonanceMimickers of cirrhosisMorphological abnormalities

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Area of Science:

  • Radiology
  • Gastroenterology
  • Medical Imaging

Background:

  • Cirrhosis diagnosis relies on hepatic morphological changes.
  • Certain conditions can present with appearances similar to cirrhosis.
  • Accurate differentiation is crucial for patient management.

Purpose of the Study:

  • To review CT and MRI findings of hepatic morphology in cirrhosis.
  • To describe and illustrate conditions that mimic cirrhosis.
  • To provide diagnostic tips for differentiating these conditions.

Main Methods:

  • Pictorial essay format.
  • Review of CT and MRI appearances of liver morphology.
  • Inclusion of various cirrhotic and non-cirrhotic conditions.

Main Results:

  • Detailed descriptions of imaging findings for cirrhosis.
  • Illustrations and explanations of mimickers such as congenital hepatic fibrosis, Caroli disease, Budd-Chiari Syndrome, hepatoportal sclerosis, cavernous transformation of the portal vein, pseudocirrhosis, acute liver failure, post-therapeutic changes, schistosomiasis, and oriental cholangiohepatitis.
  • Key features for differential diagnosis are highlighted.

Conclusions:

  • Recognizing specific hepatic morphological changes is key for diagnosing cirrhosis.
  • Awareness of cirrhotic mimickers on imaging is essential for accurate diagnosis.
  • This review aids radiologists in differentiating cirrhosis from other pathologies.