Related Experiment Video
Updated: Feb 20, 2026

10:04
Sample Drift Correction Following 4D Confocal Time-lapse Imaging
Published on: April 12, 2014
17.0K
Optically coherent image formation and denoising using a plug and play inversion framework
Applied Optics
|October 20, 2017
Summary
We developed a new framework for coherent imaging that effectively reduces noise using Gaussian denoising algorithms (GDAs). This method significantly improves image reconstruction accuracy compared to standard techniques.
Area of Science:
- Optics
- Image Processing
- Signal Processing
Background:
- Optically coherent imaging systems face performance limitations due to measurement and speckle noise.
- Speckle noise in coherent imaging is signal-dependent and follows an exponential distribution, posing challenges for traditional noise reduction methods.
Purpose of the Study:
- To develop an image formation framework for maximum a posteriori (MAP) estimation in coherent imaging.
- To enable the use of Gaussian denoising algorithms (GDAs) for mitigating noise in coherent imaging without modification.
- To compare the performance of various GDAs using simulated and experimental data.
Main Methods:
- Development of a novel image formation framework based on MAP estimation.
- Application of unmodified Gaussian denoising algorithms (GDAs) to address noise in coherent imaging.
- Comparative analysis of different GDAs using both simulated and experimental coherent imaging data.
Main Results:
- The proposed framework successfully mitigates exponentially distributed and signal-dependent noise.
- Gaussian denoising algorithms (GDAs) can be directly applied within the new framework.
- The framework demonstrates robustness to noise and significantly reduces reconstruction error compared to standard inversion methods.
Conclusions:
- The developed image formation framework enhances the performance of optically coherent imaging systems.
- The framework provides a robust and effective method for noise reduction in coherent imaging.
- This approach offers a significant improvement in image reconstruction accuracy for coherent imaging applications.
Related Concept Videos
Deconvolution
623
Deconvolution, also known as inverse filtering, is the process of extracting the impulse response from known input and output signals. This technique is vital in scenarios where the system's characteristics are unknown, and they must be inferred from the observable signals.
Deconvolution involves several mathematical techniques to derive the impulse response. One common approach is polynomial division. In this method, the input and output sequences are treated as coefficients of...
Deconvolution involves several mathematical techniques to derive the impulse response. One common approach is polynomial division. In this method, the input and output sequences are treated as coefficients of...
623
Phase Contrast and Differential Interference Contrast Microscopy
14.6K
Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
14.6K
Imaging Biological Samples with Optical Microscopy
11.4K
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
11.4K
Interference and Diffraction
52.8K
Interference is a characteristic phenomenon exhibited by waves. When two electromagnetic waves interact with their peaks and troughs coinciding, a resulting wave with enhanced amplitude is produced. This is known as constructive interference. In this case, the two waves interacting are in phase with each other.
52.8K
Reconstruction of Signal using Interpolation
773
Signal processing techniques are essential for accurately converting continuous signals to digital formats and vice versa. When a continuous signal is sampled with a period T, the resulting sampled signal exhibits replicas of the original spectrum in the frequency domain, spaced at intervals equal to the sampling frequency. To handle this sampled signal, a zero-order hold method can be applied, which creates a piecewise constant signal by retaining each sample's value until the next...
773
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)
1.1K
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT) is an advanced Nuclear Magnetic Resonance (NMR) technique specifically designed to detect and enhance the signals of low-abundance nuclei, such as carbon-13 and nitrogen-15, in small molecules. The fundamental principle behind INEPT is the transfer of polarization from a more abundant and highly polarizable nucleus, typically hydrogen-1, to the low-abundance nucleus of interest. This process effectively boosts the NMR signal of the...
1.1K
