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Fluorescence properties of doxorubicin coupled carbon nanocarriers
Abstract:
The effect of graphene oxide (GO) and nanodiamond (ND) is investigated on the spectral properties of doxorubicin (DOX) fluorescence emissions in the form of (DOX+GO) and (DOX+ND) biomaterials. It is shown that carbon nanostructure additives lead to sensible blueshifts, due to their optical properties and surface functionality. The quenching coefficient KND is obtained to be KND=0.043 (μg/ml)-1 and KGO=0.342 (μg/ml)-1 in DOX solutions. In general, Stern-Volmer attests that excited (DOX+GO) strongly quenches with respect to that of (DOX+ND) regarding its privileged bonding affinity.
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