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Design of a Biocompatible Drug-Eluting Tracheal Stent in Mice with Laryngotracheal Stenosis
Published on: January 21, 2020
[Laryngotracheal stenosis in children]
1Department of Otorhinolaryngology, Beijing Children's Hospital, Capital Medical University Beijing Key Laboratory for Pediatric Diseases of Otorhinolaryngology, Head and Neck Surgery, Beijing 100045, China.
Abstract:
Laryngotracheal stenosis includes congenital laryngotracheal stenosis and secondary laryngotracheal stenosis. Congenital laryngotracheal anomalies are rare, accounting for 0.3%-1.0% of all laryngotracheal stenosis(LTS). Despite the management of pediatric LTS over the past 30 years had been considerable improved, primary surgery still failed in a significant number of complex LTS cases. In some severe LTS cases combined with glottic stenosis, the primary surgery failed around 30%, even with the latest available techniques. Children with LTS usually need multiple operations, and need the tracheostomy tube for months or even years. Therefore, the etiology, clinical features, diagnosis and treatment of laryngotracheal stenosis are summarized in this paper.
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