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Updated: Feb 20, 2026

Transgenic Rodent Assay for Quantifying Male Germ Cell Mutant Frequency
Published on: August 6, 2014
Out of the testis: biological impacts of new genes
Kevin G Nyberg1, Richard W Carthew1
1Department of Molecular Biosciences, Northwestern University, Evanston, Illinois 60208, USA.
Abstract:
The study of newly evolved genes has long fascinated biologists, but large-scale studies of their expression dynamics and molecular function have provided conflicting interpretations of their biological impact. In this issue of Genes & Development, Kondo and colleagues (pp. 1841-1846) use extensive transcriptomic resources and current CRISPR/Cas9 technology to re-examine the functional impact of newly evolved genes in Drosophila and find evidence of their biological impact on male reproduction.
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