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Mussel-mimetic hydrogels with defined cross-linkers achieved via controlled catechol dimerization exhibiting tough
Pengchao Zhao1, Kongchang Wei, Qian Feng
1Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong, People's Republic of China. lbian@cuhk.edu.hk.
Chemical Communications (Cambridge, England)
|October 21, 2017
Abstract:
The engineering of catechol-based hydrogels to bind to wet biological tissues with high adhesion energy remains a challenge. Herein, fast quinone-nucleophile coupling and dynamic boronate ester bond were used to enhance the interfacial adhesion and bulk cohesion of our dual-crosslinked hydrogels, respectively, for fabricating mussel-mimetic tough adhesives.
