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Nanoscale Imaging Reveals Big Role for Iron in Alzheimer's Disease
Scott Ayton1, Simon A James1, Ashley I Bush1
1Melbourne Dementia Research Centre, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia.
Cell Chemical Biology
|October 21, 2017
Abstract:
In this issue of Cell Chemical Biology, Telling et al. (2017) apply advanced X-ray microscopy techniques to reveal magnetite iron species in plaques from a mouse model of Alzheimer's disease. The characterization of abnormal iron chemistry in the disease model highlights the potential for iron to combine with the β-amyloid peptide and accelerate the disease process.

