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Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

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The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
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Appendicitis-II: Diagnostic Studies and Management01:29

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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
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Acute Pancreatitis II: Clinical Manifestations and Management01:30

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Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
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Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
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Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
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Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
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Familial history aggregation on acute appendicitis.

Francesc Simó Alari1, Israel Gutierrez1, Judit Gimenéz Pérez2

  • 1General surgery, Centre hospitalier du val d'Ariege, Foix, France.

BMJ Case Reports
|October 22, 2017
PubMed
Summary

A family history of acute appendicitis significantly increases the risk of developing the condition. Clinicians should ask about family history to improve diagnosis of acute appendicitis.

Keywords:
gastrointestinal surgerygeneral practice / family medicinegeneral surgery

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Area of Science:

  • Surgical Procedures
  • Genetics and Heredity
  • Pediatric Surgery

Background:

  • Appendectomy is a common surgical procedure, with a 7% lifetime risk, particularly in adolescents and young adults.
  • Genetic factors are increasingly recognized as influencing appendicitis development and severity.
  • A family history of appendicitis is associated with a threefold increase in relative risk.

Observation:

  • A notable case involved six out of nine siblings (66.6%) diagnosed with acute appendicitis.
  • Five of these siblings were treated at the reporting hospital.
  • This familial aggregation highlights a potential genetic predisposition.

Findings:

  • Family history is a significant risk factor for acute appendicitis.
  • Genetic influence plays a role in the predisposition and severity of appendicitis.
  • A positive family history triples the relative risk of developing appendicitis.

Implications:

  • Inquiring about family history is crucial for accurate diagnosis of acute abdominal pain.
  • Clinicians should consider appendicitis in patients with a family history of the condition.
  • Enhanced diagnostic accuracy can be achieved by incorporating family history into patient assessments.