Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Smart Hydrogels for Craniofacial Regeneration.

Cells·2026
Same author

Bioengineering Interventions to Enhance the Capacity of the Gut Microbiota in Controlling Food Allergies.

Life (Basel, Switzerland)·2026
Same author

VEGF-A-Mediated Differentiation of Gingival Stem Cells to Endothelial Progenitor-Like Cells.

Tissue engineering. Part A·2026
Same author

Comprehensive evaluation of critical-size calvarial defect in athymic rat model.

Frontiers in physiology·2025
Same author

The Therapeutic Scope of Orofacial Mesenchymal Stem Cells.

Bioengineering (Basel, Switzerland)·2025
Same author

Floss-based vaccination targets the gingival sulcus for mucosal and systemic immunization.

Nature biomedical engineering·2025

Related Experiment Video

Updated: Feb 20, 2026

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

10.1K

Three-dimensional macroporous materials for tissue engineering of craniofacial bone.

Akhilesh Kumar Shakya1, Umadevi Kandalam2

  • 1Department of Chemical Engineering, Texas Tech University, Lubbock, TX, USA.

The British Journal of Oral & Maxillofacial Surgery
|October 24, 2017
PubMed
Summary

Macroporous scaffolds offer promising solutions for repairing critical-size craniofacial bone defects. This review highlights advanced scaffold technologies and biomaterials for enhanced bone regeneration.

Keywords:
Bioactive foamsCompositeCraniofacial bone regenerationCryogelsHydrogelsMacroporous materials

More Related Videos

Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer
07:05

Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer

Published on: September 22, 2015

10.5K
Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs
10:19

Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs

Published on: August 8, 2022

2.5K

Related Experiment Videos

Last Updated: Feb 20, 2026

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

10.1K
Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer
07:05

Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer

Published on: September 22, 2015

10.5K
Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs
10:19

Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs

Published on: August 8, 2022

2.5K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Craniofacial Surgery

Background:

  • Critical-size defects in the craniofacial region pose significant reconstructive challenges.
  • Current treatments for craniofacial bone defects have limitations.
  • Tissue engineering presents a viable future surgical option.

Purpose of the Study:

  • To review current research on macroporous scaffolds for craniofacial bone defect repair.
  • To evaluate various biomaterials and 3D-printed scaffold technologies.
  • To assess the potential of these scaffolds in bone regeneration.

Main Methods:

  • Systematic literature review of research papers on macroporous scaffolds, stem cells, and growth factors.
  • Selection based on titles, abstracts, and full-text assessment.
  • Focus on craniofacial defects (mandibular, calvarial) and technological advancements.

Main Results:

  • Macroporous scaffolds with interconnected pores are crucial for craniofacial bone regeneration.
  • Diverse natural and synthetic biomaterials are utilized for scaffold development.
  • 3D-printed scaffolds represent a key technological advancement.

Conclusions:

  • Tissue engineering methods using macroporous scaffolds show great potential for craniofacial bone defect repair.
  • Advanced scaffold designs and biomaterials are vital for successful bone regeneration.
  • Further research into these technologies could revolutionize craniofacial reconstruction.