Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

17.1K
The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
17.1K
Atomic Force Microscopy01:08

Atomic Force Microscopy

4.6K
Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
4.6K
Scanning Electron Microscopy01:07

Scanning Electron Microscopy

5.6K
A scanning electron microscope (SEM) is used to study the surface features of a sample by using an electron beam that scans the sample surface in a two-dimensional manner. Typically, areas between ~1 centimeter to 5 micrometers in width can be imaged. SEM can be used to image bacteria, viruses, tissues as well as larger samples like insects. Conventional SEM gives a magnification ranging from 20X to 30,000X and spatial resolution of 50 to 100 nanometers.
Fundamental Principles
Accelerated...
5.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tissue geometry drives deterministic organoid patterning.

Science (New York, N.Y.)·2022
Same author

Controlled Indentation Flaws for the Construction of Toughness and Fatigue Master Maps.

Journal of research of the National Bureau of Standards (1977)·2021
Same author

Tracking Defects and Microstructural Heterogeneities in Meso-Scale Tensile Specimens Excised from Additively Manufactured Parts.

Experimental mechanics·2020
Same author

Recent Advances in Micro, Nano, and Cell Mechanics.

Experimental mechanics·2019
Same author

Material Flaw Populations and Component Strength Distributions in the Context of the Weibull Function.

Experimental mechanics·2019
Same author

Rapid detection of equine infectious anaemia virus nucleic acid by insulated isothermal RT-PCR assay to aid diagnosis under field conditions.

Equine veterinary journal·2018
Same journal

The In-Situ Mechanics of the Tricuspid Valve: Strain Heterogeneity and Anisotropy via 3D Digital Image Correlation.

Experimental mechanics·2026
Same journal

Image-based Evaluation of Cutting Forces During Ultrasonic Cutting of Bone.

Experimental mechanics·2026
Same journal

Evaluation of Recyclable Multilayer Packaging Designs Utilising Controlled Interlayer Adhesion.

Experimental mechanics·2025
Same journal

Influence of Temperature, Strain Rate, and Condition on the Mechanical Response of an AlSi-PES Abradable.

Experimental mechanics·2025
Same journal

An <i>In-Situ</i> Corrosion Small Punch Test for Developing Stress Corrosion Cracking in Stainless Steel.

Experimental mechanics·2025
Same journal

An Experimental Method for Fatigue Testing Cast Iron Water Pipes Using Combined Internal Water Pressure and Bending Loads.

Experimental mechanics·2025
See all related articles

Related Experiment Video

Updated: Feb 20, 2026

Quantitative and Qualitative Examination of Particle-particle Interactions Using Colloidal Probe Nanoscopy
13:15

Quantitative and Qualitative Examination of Particle-particle Interactions Using Colloidal Probe Nanoscopy

Published on: July 18, 2014

11.5K

Quantitative Scanning Probe Microscopy for Nanomechanical Forensics.

F W DelRio1, R F Cook2

  • 1Applied Chemicals and Materials Division, Material Measurement Laboratory, National Institute of Standards and Technology, Boulder, CO 80305, USA.

Experimental Mechanics
|October 24, 2017
PubMed
Summary
This summary is machine-generated.

Atomic force microscopy (AFM) quantifies physical properties of forensic evidence like hair, inks, fingerprints, and explosives. This advanced technique enhances information extraction and evidentiary value for critical forensic investigations.

Keywords:
Explosive materialsFingerprint residueForensic scienceMechanical propertiesQuestioned documentsScanning probe microscopyTrace evidence

More Related Videos

Author Spotlight: Introduction to Active Probe Atomic Force Microscopy with Quattro-Parallel Cantilever Arrays
05:04

Author Spotlight: Introduction to Active Probe Atomic Force Microscopy with Quattro-Parallel Cantilever Arrays

Published on: June 13, 2023

2.5K
Atomic Force Microscopy Cantilever-Based Nanoindentation: Mechanical Property Measurements at the Nanoscale in Air and Fluid
08:58

Atomic Force Microscopy Cantilever-Based Nanoindentation: Mechanical Property Measurements at the Nanoscale in Air and Fluid

Published on: December 2, 2022

3.8K

Related Experiment Videos

Last Updated: Feb 20, 2026

Quantitative and Qualitative Examination of Particle-particle Interactions Using Colloidal Probe Nanoscopy
13:15

Quantitative and Qualitative Examination of Particle-particle Interactions Using Colloidal Probe Nanoscopy

Published on: July 18, 2014

11.5K
Author Spotlight: Introduction to Active Probe Atomic Force Microscopy with Quattro-Parallel Cantilever Arrays
05:04

Author Spotlight: Introduction to Active Probe Atomic Force Microscopy with Quattro-Parallel Cantilever Arrays

Published on: June 13, 2023

2.5K
Atomic Force Microscopy Cantilever-Based Nanoindentation: Mechanical Property Measurements at the Nanoscale in Air and Fluid
08:58

Atomic Force Microscopy Cantilever-Based Nanoindentation: Mechanical Property Measurements at the Nanoscale in Air and Fluid

Published on: December 2, 2022

3.8K

Area of Science:

  • Forensic Science
  • Materials Science
  • Surface Science

Background:

  • Forensic science requires advanced analytical techniques to characterize diverse evidence types.
  • Quantifying physical properties of evidence is crucial for establishing its evidentiary value.
  • Existing methods may lack the resolution or sensitivity needed for detailed evidence analysis.

Purpose of the Study:

  • To evaluate the utility of Atomic Force Microscopy (AFM) for analyzing forensic evidence.
  • To measure indentation modulus (Ms) and pull-off force (Fpo) of various evidence types.
  • To demonstrate AFM's capability in forensic science applications.

Main Methods:

  • Atomic Force Microscopy (AFM) was employed to perform nanoindentation and force spectroscopy.
  • Measurements of indentation modulus (Ms) and pull-off force (Fpo) were conducted.
  • Case studies included hair, questioned documents (inks), fingerprints, and explosive particle-surface interactions.

Main Results:

  • Hair: Conditioner and bleach altered Ms and Fpo.
  • Questioned Documents: Ballpoint pen ink showed less variation in Ms and Fpo than printer ink.
  • Fingerprints: Maximum height and Fpo decreased over three days.
  • Explosive Particles: Fabrics showed similar Ms but different Fpo.

Conclusions:

  • AFM effectively quantifies physical properties of diverse forensic evidence.
  • The technique provides valuable data to expand information extracted from evidence.
  • AFM addresses federal agency needs for improved evidence analysis and quantification of evidentiary value.