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The effects of adrenergic agonists and age on lipogenesis in avian hepatocytes
R B Harris1, M J Neal, R J Martin
1Department of Foods and Nutrition, University of Georgia, Athens 30602.
Abstract:
1. Adrenergic inhibition of lipogenesis was examined in vitro using hepatocytes isolated from chickens 2-9 weeks old. 2. Lipogenesis was inhibited by beta 1, beta 2 and alpha 1 agonists. Greatest inhibition occurred when more than one type of receptor was stimulated. 3. Clonidine (alpha 2-agonist) may have stimulated lipogenesis. 4. Responsiveness to the agonists decreased as the chickens got older.