Profiling a multiplex short tandem repeat loci from human urine with use of low cost on-site technology for
Abstract:
This work focuses on the development of a sophisticated technique via STR typing to unequivocally verify the authenticity of urine samples before sent to laboratories. STR profiling was conducted with the CSF1PO, TPOX, TH01 Multiplex System coupled with a smartphone-based detection method. The promising capability of the method to identify distinct STR profiles from urine of different persons opens the possibility to conduct sample authenticity tests. On-site STR profiling could be realized with a self-contained autonomous device with an integrated PCR microchip shown hereby.
Related Concept Videos
Strategies of Self-Presentation II: Self-Verification
Urine Studies II: Urine Culture and Sensitivity Test
Self-Evaluation: Self-Enhancement and Self-Verification
Filtration and Urine Formation
Root Loci for Positive-Feedback Systems
The construction rules for the root locus in positive feedback systems are similar to those in...
Physiology of Urine Formation
Glomerular Filtration
The first stage in urine formation is glomerular filtration. Each kidney contains approximately 1 million nephrons, the functional units of filtration, with a...


