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Updated: Feb 20, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Automatic diagnosis of melanoma using linear and nonlinear features from digital image
Abstract:
Melanoma is the most serious type of skin cancer and causes more deaths than other forms of skin cancer. It is a tiny small malignant mole that is usually black or brown but also appears in other color patterns. Early detection of melanoma is key as this is the time period when it is most likely to be cured. Due to the advancement of smartphone technology, automatic and efficient detection of melanoma mole using a smartphone is an active area of research. In this study, we developed an automatic melanoma diagnosis system using images captured from the digital camera. Our work differs from other studies in the area of segmentation of melanoma region and consideration of non-linear features for classification of malignant and benign melanoma. In this paper, a combination of Otsu and k-means clustering segmentation methods are applied to automatically segment and extract the borders of affected region with satisfactory accuracy. Also, we explored and extracted different non-linear features along with color and texture features existed in literature from the lesion mole. The effectiveness of these features was predicted with a machine learning model consisting of five different classifiers. Our model predicted the diagnosis of mole with an accuracy of 89.7%, i.e., around 10% more than reported results by others (to the best of our knowledge) with the same database.

