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Concurrent Computer-Aided Detection Improves Reading Time of Digital Breast Tomosynthesis and Maintains
Richard A Benedikt1, Justin E Boatsman1, Cynthia A Swann1
11 Intrinsic Imaging, LLC, 8401 Datapoint, Ste 600, San Antonio, TX 78229.
AJR. American Journal of Roentgenology
|October 25, 2017
Summary
Computer-aided detection (CAD) significantly reduced reading time for digital breast tomosynthesis (DBT) by 29.2% without compromising interpretation performance. This advancement enhances efficiency in breast cancer screening using DBT technology.
Area of Science:
- Radiology and Medical Imaging
- Artificial Intelligence in Healthcare
- Breast Cancer Diagnostics
Background:
- Digital breast tomosynthesis (DBT) offers improved accuracy over traditional mammography but increases radiologist reading time.
- Efficient interpretation of DBT images is crucial for timely breast cancer diagnosis and patient management.
Purpose of the Study:
- To evaluate the impact of concurrent computer-aided detection (CAD) on radiologist reading time for DBT.
- To assess whether the use of CAD affects the interpretation performance (accuracy) in DBT image analysis.
Main Methods:
- A CAD system was developed to identify suspicious soft-tissue densities in DBT images.
- Twenty radiologists retrospectively reviewed 240 DBT cases (68 malignancies) with and without concurrent CAD in a multireader multicase crossover study.
- Reading time and performance metrics (ROC AUC, sensitivity, specificity, recall rate) were compared.
Main Results:
- Concurrent CAD use reduced reading time by 29.2% (p < 0.01).
- Reader performance, measured by ROC AUC, was noninferior with CAD (mean AUC increased from 0.841 to 0.850).
- Sensitivity showed a trend of improvement, particularly for soft-tissue densities, while specificity and recall rates remained comparable.
Conclusions:
- Concurrent CAD integration with DBT significantly accelerates image interpretation.
- The use of CAD with DBT maintains or potentially improves diagnostic performance, offering a more efficient screening tool.

