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Recent Progress in Optical Biosensors Based on Smartphone Platforms.

Zhaoxin Geng1, Xiong Zhang2, Zhiyuan Fan3

  • 1School of Information Engineering, Minzu University of China, Beijing 100081, China. Zxgeng@muc.edu.cn.

Sensors (Basel, Switzerland)
|October 26, 2017
PubMed
Summary
This summary is machine-generated.

Smartphone optical biosensors leverage complementary metal oxide semiconductor (CMOS) cameras for point-of-care testing (POCT). This review covers recent advancements in imaging and spectrometry-based smartphone platforms for chemical and biological diagnostics.

Keywords:
biosensormicroscopeopticalsmartphonesspectrometry

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Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Optical Sensing

Background:

  • Smartphone hardware, particularly complementary metal oxide semiconductor (CMOS) cameras, has rapidly advanced.
  • This progress has enabled the development of numerous optical biosensors integrated with smartphone platforms.
  • These advancements are driving the evolution of point-of-care testing (POCT).

Purpose of the Study:

  • To critically review recent progress in smartphone-integrated platforms for biosensing and diagnostics.
  • To focus on imaging-based and spectrometry-based detection techniques.
  • To evaluate the analytical performance and implementation complexity of these platforms.

Main Methods:

  • Review of recent scientific literature on smartphone-based biosensing platforms.
  • Analysis of imaging-based techniques utilizing smartphone microscopes for microscale analysis.
  • Evaluation of spectrometry-based techniques for probing molecular reactions and changes.

Main Results:

  • Smartphone platforms are effectively used for both imaging-based (microscale analysis) and spectrometry-based (molecular probing) detection.
  • These integrated platforms are being applied across a wide range of chemical experiments and biological diagnostics.
  • Recent developments focus on enhancing analytical performance and simplifying platform implementation.

Conclusions:

  • Smartphone-integrated optical biosensors represent a significant advancement in POCT.
  • Both imaging and spectrometry techniques show great potential for diverse applications in chemical and biological sciences.
  • Future research should continue to optimize performance and usability for widespread adoption.