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Updated: Feb 20, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Born Into Addiction: Neonatal Abstinence Syndrome and Pediatric Dentistry
1Assistant professor, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA;,
Insights
Neonatal abstinence syndrome (NAS), a withdrawal in infants from opioid exposure, is increasing. Pediatric dentists must recognize NAS
Area of Science:
- Public Health
- Pediatric Dentistry
- Neonatal Medicine
Background:
- Opioid-involved deaths and drug overdose rates are rising nationally.
- Neonatal abstinence syndrome (NAS) is a critical condition in infants exposed to opioids during pregnancy.
- Current treatment protocols for NAS lack national, evidence-based standardization.
Purpose of the Study:
- To present background information on the incidence of NAS.
- To highlight potential dental development issues and developmental delays in children with NAS.
- To inform healthcare providers, particularly pediatric dentists, about NAS implications.
Main Methods:
- Review of existing literature on neonatal abstinence syndrome.
- Analysis of the impact of maternal opioid use on infant health.
- Discussion of challenges in managing NAS and its dental sequelae.
Main Results:
- NAS affects opioid-exposed infants, leading to postnatal drug withdrawal.
- Children with NAS may experience dental development issues and delays.
- Standard behavior guidance techniques may be less effective for these children.
Conclusions:
- Pediatric dentists need awareness of NAS and its potential oral health consequences.
- Prescription drug monitoring programs can aid in identifying at-risk patients.
- Further research is needed for evidence-based treatment protocols for NAS.
Abstract:
Drug overdose and opioid-involved deaths continue to increase across the United States. An end-condition related to opioid abuse is neonatal abstinence syndrome (NAS). The implications for pregnant or post-partum women using an opioid, whether prescribed or illicit, can have significant effects on their infant. First described in the 1970s, NAS is defined as a postnatal drug withdrawal syndrome that primarily occurs in opioid-exposed infants. There are no nationally accepted, evidence-based treatment protocols for these infants. Pediatric dentists should be cognizant of potential dental development issues and developmental delays in children with NAS. Basic behavior guidance techniques, such as tell-show-do, may not be as effective. In addition, adherence to prescription drug monitoring programs can help identify patients who may have received multiple opioids, alerting the provider to possible misuse or abuse. The purpose of this paper was to provide background information on the incidences and potential dental implications for children with neonatal abstinence syndrome.
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