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Updated: Feb 20, 2026

Photodynamic Therapy with Blended Conducting Polymer/Fullerene Nanoparticle Photosensitizers

Photodynamic Therapy with Blended Conducting Polymer/Fullerene Nanoparticle Photosensitizers

Published on: October 28, 2015

Targeted Nanomaterials for Phototherapy.

Upendra Chitgupi¹, Yiru Qin¹, Jonathan F Lovell¹

¹Department of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, New York, USA.

Nanotheranostics

|October 27, 2017

Summary

Molecularly targeted photosensitizers and nanoparticles enhance phototherapy selectivity. This review summarizes recent targeted nanomaterials for improved light-based treatment efficacy.

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Area of Science:

Biomedical Engineering
Nanotechnology
Photomedicine

Background:

Phototherapies utilize light irradiation for treating target tissues.
Developing molecularly targeted photosensitizers and nanoparticles improves treatment selectivity and potency.
Active targeting leverages ligand-receptor interactions for enhanced accumulation in target tissues.

Purpose of the Study:

To review recent advancements in targeted nanomaterials for phototherapy.
To highlight the application of various targeting ligands in enhancing phototherapy efficacy.

Main Methods:

Literature review of targeted nanomaterials in phototherapy.
Analysis of different targeting ligands (peptides, proteins, aptamers, small molecules).
Summarization of recent examples of nanomaterial-based targeted phototherapy.

Keywords:

cancer.photodynamic therapy photosensitizers photothermal therapy targeting

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Main Results:

Numerous molecularly targeted photosensitizers and photoactive nanoparticles have been developed.
Targeting ligands facilitate improved accumulation of therapeutic agents in target tissues.
Recent studies showcase diverse targeted nanomaterials for enhanced phototherapy.

Conclusions:

Targeted nanomaterials represent a promising strategy to improve the selectivity and efficacy of phototherapies.
The development of novel targeting ligands and nanomaterial designs continues to advance the field of photomedicine.