Related Experiment Video
Updated: Feb 20, 2026
07:13
Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
5.3K
Nutrition and the transplant candidate
Vera C Mazurak1, Puneeta Tandon2, Aldo J Montano-Loza2
1Divisions of Human Nutrition.
Summary
Malnutrition and sarcopenia are common in liver transplant candidates, negatively impacting outcomes. Early assessment and treatment of muscle wasting are crucial for improving survival and reducing complications.
Area of Science:
- Hepatology
- Transplantation Medicine
- Nutritional Science
Background:
- Cirrhosis is a leading reason for liver transplantation (LT).
- Malnutrition, particularly muscle wasting (sarcopenia), affects over two-thirds of patients awaiting LT.
- Sarcopenia is linked to worse survival and increased complications before and after LT.
Purpose of the Study:
- To review current diagnostic methods for malnutrition and sarcopenia in LT candidates.
- To present the incidence and clinical impact of malnutrition and sarcopenia in cirrhosis and post-LT.
- To discuss therapeutic strategies for malnutrition and muscle wasting in LT candidates.
Main Methods:
- Review of current literature on nutritional assessment in cirrhosis.
- Analysis of diagnostic tools for evaluating muscle abnormalities.
- Discussion of therapeutic interventions for malnutrition.
Main Results:
- Malnutrition and sarcopenia are prevalent and significantly impact LT outcomes.
- Cross-sectional imaging is a useful, objective marker for nutritional status.
- Despite high prevalence, nutritional assessment is often overlooked.
Conclusions:
- Addressing malnutrition and sarcopenia is vital for optimizing LT candidate health.
- Therapeutic strategies should focus on improving muscle mass to enhance pre- and post-transplant outcomes.
- Standardized nutritional assessment protocols are needed for LT candidates.
Related Concept Videos
01:28Kidney Transplant I: Introduction
537
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
537
01:16Kidney Transplant III: Nursing Management
424
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
424
01:26Kidney Transplant II: Surgical Procedure
492
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
492
01:24Tissue Transplantation
1.1K
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
1.1K
01:22Bone Marrow Sampling and Transplants
1.7K
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
1.7K
01:28Chronic Kidney Disease III: Interprofessional Care
495
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
495