Related Experiment Video
Updated: Feb 20, 2026

07:54
Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
7.3K
Differences between peritoneal and pleural mesothelioma in Lombardy, Italy
Carolina Mensi1, Marco Mendola2, Barbara Dallari1
1Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy.
Cancer Epidemiology
|October 27, 2017
Summary
Peritoneal mesothelioma (PEM) and pleural mesothelioma (PLM) share asbestos links. Higher rates of asbestosis and asbestos cement work in PEM cases suggest high asbestos exposure may cause peritoneal mesothelioma.
Area of Science:
- Environmental Epidemiology
- Occupational Health
- Oncology
Background:
- Mesothelioma, a rare cancer, affects the pleura or peritoneum.
- Lombardy, Italy, has a Mesothelioma Registry tracking cases.
Purpose of the Study:
- To investigate the characteristics of peritoneal mesothelioma (PEM) and pleural mesothelioma (PLM).
- To explore the association between asbestos exposure and these mesothelioma types.
Main Methods:
- Analysis of 300 PEM and 5011 PLM cases diagnosed between 2000-2014 in Lombardy.
- Investigation of asbestos exposure, asbestosis, and pleural plaques in cases.
Main Results:
- PEM incidence rates were 1.2 (men) and 0.9 (women) per million person-years.
- Asbestosis and pleural plaques were more common in PEM cases.
- Higher proportion of PEM cases had worked in asbestos cement production.
Conclusions:
- Pleural plaques in PEM cases confirm asbestos association.
- Asbestosis and asbestos cement work suggest high asbestos exposure may cause peritoneal mesothelioma.
Related Concept Videos
Pleural Disorders: Types and Brief Description
746
The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
746
Pleura of the Lungs
8.0K
The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
8.0K
Pleural Effusion II: Symptoms and Management
839
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
839
Pleural Effusion I: Introduction
4.7K
Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
4.7K
Peritoneum
10.0K
The peritoneum is a vital membrane that lines the abdominal cavity and covers most of the organs within it. It plays a crucial role in protecting the organs, providing a smooth surface for their movement, and facilitating various physiological processes. Understanding the anatomy and function of the peritoneum is essential for comprehending the complexities of the abdominal region.
Anatomy of the Peritoneum
The peritoneum is divided into two layers: the parietal peritoneum and the visceral...
Anatomy of the Peritoneum
The peritoneum is divided into two layers: the parietal peritoneum and the visceral...
10.0K

