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Related Concept Videos

Olfactory Receptors: Location and Structure01:03

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The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
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Endoscopic surgery of the olfactory cleft.

R Jankowski1, C Rumeau1, P Gallet1

  • 1Service ORL et chirurgie de la face et du cou, centre hospitalier régional universitaire de Nancy, hôpitaux de Brabois, bâtiment Louis-Mathieu, rue du Morvan, 54500 Vandœuvre-les-Nancy, France; Université de Lorraine, faculté de médecine, rue de la Forêt-de-Haye, 54500 Vandœuvre-les-Nancy, France.

European Annals of Otorhinolaryngology, Head and Neck Diseases
|October 28, 2017
PubMed
Summary

The olfactory cleft is a key site for tumors and cerebrospinal fluid (CSF) leaks. Surgical options for olfactory cleft tumors and CSF leaks offer complementary treatments to ethmoidal and skull base surgeries.

Keywords:
Anterior skull baseCerebrospinal fluid leakageEndoscopic endonasal surgeryNasal tumoursOlfactory cleft

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Area of Science:

  • Otolaryngology
  • Neurosurgery
  • Oncology

Background:

  • The olfactory cleft is a common origin for various tumors, including respiratory epithelial adenomatoid hamartoma and adenocarcinoma.
  • It is also the site of cerebrospinal fluid (CSF) rhinorrhoea through the cribriform plate, termed cribri-rhinorrhoea.

Purpose of the Study:

  • To outline the surgical management of olfactory cleft tumors.
  • To detail the diagnostic and therapeutic approaches for cribri-rhinorrhoea.

Main Methods:

  • Olfactory cleft tumors can be resected via five distinct surgical procedures.
  • Cribri-rhinorrhoea diagnosis involves endoscopic identification of CSF originating from the cribriform plate.

Main Results:

  • Surgical interventions for olfactory cleft pathologies are complementary to ethmoidal labyrinth and anterior skull base surgery.
  • Five resection techniques exist for olfactory cleft tumors, ranging from mucosal resection to extensive skull base resections.

Conclusions:

  • Specific surgical strategies are available for olfactory cleft tumors and cribri-rhinorrhoea.
  • These surgical options represent a specialized field complementing broader ethmoidal and skull base procedures.