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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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Author Spotlight: Advancements in 3D Optical Imaging for Comprehensive Body Composition Assessment in Modern Research
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Body composition differences between adults with multiple sclerosis and BMI-matched controls without MS.

Brooks C Wingo1, Hui-Ju Young2, Robert W Motl3

  • 1Department of Occupational Therapy, University of Alabama at Birmingham, Birmingham, AL, USA; UAB/Lakeshore Research Collaborative, Birmingham, AL, USA.

Disability and Health Journal
|October 28, 2017
PubMed
Summary
This summary is machine-generated.

Men with multiple sclerosis (MS) have different body composition than those without MS, with less lean mass and more fat mass, even at the same body mass index (BMI). This highlights potential health implications for men with MS.

Keywords:
Body compositionMultiple sclerosisObesity

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Area of Science:

  • Neurology
  • Body Composition Analysis
  • Human Physiology

Background:

  • Multiple sclerosis (MS) is associated with various health conditions, particularly those linked to overweight and obesity.
  • Limited understanding exists regarding how body composition in individuals with MS compares to those without MS at equivalent body weights.

Purpose of the Study:

  • To conduct a comparative analysis of whole body and regional body composition.
  • To compare individuals with and without MS, matched for sex and body mass index (BMI).

Main Methods:

  • Dual-energy X-ray absorptiometry (DXA) was utilized to assess body composition.
  • Participants included 51 individuals with MS and 51 non-MS controls, matched for sex and BMI.
  • Evaluated parameters included total mass, lean mass, fat mass, and percent body fat (%BF) for the whole body and specific segments (arm, leg, trunk).

Main Results:

  • Men with MS exhibited significantly lower whole body lean mass and higher fat mass and %BF compared to BMI-matched men without MS.
  • Men with MS demonstrated reduced lean mass and increased fat mass in the arm, leg, and trunk regions.
  • Significantly higher %BF was observed in all three regions for men with MS compared to their non-MS counterparts.
  • No significant body composition differences were found between women with and without MS.

Conclusions:

  • Significant disparities in whole body and regional body composition exist between men with and without MS, even when matched for BMI.
  • Further investigation is warranted to explore these body composition differences, adipose tissue distribution, and their impact on the health and function of men with MS.