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Updated: Feb 20, 2026

A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats
Published on: February 20, 2021
[MANAGEMENT OF ADULT SEPTIC PATIENT IN EMERGENCY UNIT]
Abstract:
Early identification of sepsis is crucial to improve patient outcomes. Yet, sepsis can be difficult to differentiate in Emergency Unit. Sepsis treatment includes fluid resuscitation as soon as possible, starting with >1000 mL of crystalloids or 500 mL of colloids for 30 min. Acute kidney injury is a serious complication of sepsis, associated with increased mortality, prolonged hospital stay and increased cost of care. In patients with sepsis, it would be useful to have some biomarkers of early organ damage, to improve the capacity for early recognition and diagnosis of acute kidney injury.
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