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Updated: Feb 20, 2026

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
Published on: January 5, 2024
Internet-Delivered Exposure Therapy for Fibromyalgia: A Randomized Controlled Trial
Maria Hedman-Lagerlöf1, Erik Hedman-Lagerlöf1, Erland Axelsson1
1Department of Clinical Neuroscience, Division of Psychology.
Internet-delivered exposure therapy (iExp) significantly improved fibromyalgia symptoms and impact compared to a waitlist control. This accessible treatment shows sustained results, offering new hope for chronic pain management.
Area of Science:
- Psychology
- Pain Management
- Digital Health
Background:
- Fibromyalgia (FM) is a widespread, disabling chronic pain condition.
- Current treatments offer insufficient relief for many patients.
- Exposure therapy shows promise for chronic pain management.
Purpose of the Study:
- To evaluate the efficacy of Internet-delivered exposure therapy (iExp) for fibromyalgia.
- To conduct the first randomized controlled trial of exposure therapy for FM.
Main Methods:
- 140 participants with FM were randomized to a 10-week iExp or waitlist control (WLC).
- Primary outcomes included FM symptoms and impact.
- Secondary outcomes assessed fatigue, disability, quality of life, distress, avoidance, insomnia, depression, and anxiety.
Main Results:
- High data retention was observed across all time points.
- The iExp group showed large, superior improvements in FM symptoms and impact versus WLC (Cohen d=0.90).
- Significant improvements were noted in all secondary outcomes (Cohen d=0.44–1.38) with sustained effects.
Conclusions:
- Internet-delivered exposure therapy (iExp) is an efficacious treatment for fibromyalgia compared to no treatment.
- The Internet format enhances accessibility of psychological treatments for FM patients.
- Further research with active control groups is recommended.
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