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Multicentric high grade oligodendroglioma: a rare entity
Atul Vats1, Amit Amit1, Paresh Doshi2
1Neurosurgery, University Hospital Coventry, Coventry, UK.
British Journal of Neurosurgery
|October 29, 2017
Summary
This study reports a rare case of multicentric high-grade oligodendroglioma in a 74-year-old male. The brain tumor, diagnosed via biopsy, presented as multiple ring-enhancing lesions on MRI.
Area of Science:
- Neuro-oncology
- Neurosurgery
- Neuropathology
Background:
- High-grade oligodendroglioma is a primary brain tumor typically presenting as a single lesion.
- Multicentric occurrence of oligodendroglioma is exceptionally rare in clinical practice.
Observation:
- A 74-year-old male presented with right upper limb weakness and motor aphasia.
- Brain MRI revealed three discrete ring-enhancing lesions, suggestive of multiple neoplastic processes.
- An awake craniotomy and biopsy were performed for histopathological diagnosis.
Findings:
- Histopathological examination confirmed the lesions as grade III Oligodendroglioma.
- This represents a rare instance of multicentric high-grade oligodendroglioma, a presentation not previously documented in medical literature.
Implications:
- This case expands the understanding of oligodendroglioma's potential clinical presentations.
- Highlights the importance of comprehensive diagnostic evaluation for multiple brain lesions.
- Suggests further research into the etiology and management of multicentric gliomas.
