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Updated: Feb 19, 2026
09:03
Human Mesenchymal Stem Cell Processing for Clinical Applications Using a Closed Semi-Automated Workflow
Published on: March 17, 2023
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Cytotherapy using stromal cells: Current and advance multi-treatment approaches
Pravin Shende1, Hunny Gupta1, R S Gaud1
1Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKM's NMIMS, Vile Parle (W), Mumbai, India.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|October 29, 2017
Summary
Mesenchymal stem cells (MSCs) are key to understanding human development and offer therapeutic potential for various diseases. This review explores MSCs
Area of Science:
- Stem Cell Biology
- Regenerative Medicine
- Developmental Biology
Background:
- Stem cells are crucial for understanding human development and differentiation.
- They possess self-renewal and differentiation capabilities.
- Mesenchymal stem cells (MSCs) have been utilized in cellular therapy for over a decade.
Purpose of the Study:
- To review the history and types of stem cells.
- To detail the targets and mechanisms of MSCs.
- To highlight MSCs' potential in regenerative medicine and immunomodulation.
Main Methods:
- Literature review of stem cell research.
- Analysis of MSC differentiation potential.
- Examination of therapeutic applications and mechanisms.
Main Results:
- MSCs can differentiate into various cell types (osteoblasts, chondrocytes, myocytes, adipocytes, neurons).
- MSCs are versatile for treating conditions like spinal cord injury, diabetes, Parkinsonism, and cardiac disorders.
- MSCs offer benefits beyond regeneration, including immunomodulation.
Conclusions:
- MSCs are a significant future therapeutic tool for regenerative medicine.
- Their applications extend to treating a wide range of diseases.
- Further research into MSC mechanisms will enhance their clinical utility.
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