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Updated: Feb 19, 2026

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Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
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Delayed complications from expanded endonasal surgery for intracranial tumors
Mathew N Geltzeiler1,2, Eric W Wang1
1Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Current Opinion in Otolaryngology & Head and Neck Surgery
|October 31, 2017
Summary
Delayed complications after endoscopic endonasal skull base surgery are uncommon but can impact quality of life. Recognizing and managing these sinonasal, neuroanatomic, endocrine, and vascular issues is crucial for patient care.
Area of Science:
- Neurosurgery
- Otolaryngology
- Skull Base Surgery
Background:
- Endoscopic endonasal approaches (EEA) are increasingly utilized for skull base pathologies.
- While generally safe, delayed complications (>1 month postoperatively) can occur.
Purpose of the Study:
- To review current advancements in the management of delayed complications following EEA.
- To categorize and discuss sinonasal, neuroanatomic, endocrine, and vascular delayed complications.
Main Methods:
- Literature review of recent advancements in EEA outcomes.
- Analysis of delayed complication types and their impact on quality of life (QOL).
Main Results:
- EEA generally improves patient QOL.
- Delayed complications, including sinonasal dysfunction, encephaloceles, and endocrinopathies, can negatively affect QOL.
- Awareness and prompt management are key.
Conclusions:
- EEA is a safe and well-tolerated procedure for selected patients.
- Recognition and management of delayed complications are essential for optimal patient outcomes.
- This review provides valuable insights for endoscopic skull base surgeons.

