Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Korotkoff Sounds01:12

Korotkoff Sounds

9.1K
Korotkoff sounds are the specific sounds heard while measuring blood pressure using a sphygmomanometer, typically with a stethoscope or a Doppler device. They are named after Russian physician Nikolai Korotkov, who first described them in 1905. These sounds correspond to turbulent blood flow in the artery as the blood pressure cuff is gradually released after inflation.
During blood pressure assessment, inflating the cuff 30 millimeters of mercury above the patient's systolic blood pressure...
9.1K
Correlation between ECG and Cardiac Cycle01:25

Correlation between ECG and Cardiac Cycle

13.2K
The electrical signals recorded on an electrocardiogram (ECG) occur before the mechanical processes of contraction and relaxation during the cardiac cycle.
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
13.2K
Electrocardiogram Fundamentals01:28

Electrocardiogram Fundamentals

1.6K
Introduction
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
1.6K
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

789
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
789
The Cardiac Cycle01:13

The Cardiac Cycle

99.3K
The heart beats rhythmically in a sequence called the cardiac cycle—a rapid coordination of contraction (systole) and relaxation (diastole).
The Process
Electrical signals—sent from the sinoatrial (SA) node in the right atrial wall to the atrioventricular (AV) node between the right atrium and right ventricle—cause both atria to simultaneously contract. When the signal reaches the AV node, it pauses for approximately a tenth of a second, allowing the atria to contract and...
99.3K
Cardiac Cycle01:29

Cardiac Cycle

13.6K
The cardiac cycle refers to the sequence of events that occur in the heart from the beginning of one heartbeat to the next. It's characterized by alternating periods of contraction (systole) and relaxation (diastole) of the heart muscles.
During the cardiac cycle, blood flow through the heart is regulated entirely by changing pressure gradients. This sequence of events begins with the heart in a state of total relaxation, known as mid-to-late diastole, during which blood passively flows from...
13.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Precision percutaneous coronary intervention.

NPJ cardiovascular health·2026
Same author

Protecting Clinical Judgment Through Shared Decision Making.

Journal of the American College of Cardiology·2026
Same author

Beyond the Cath Lab: Navigating Identity, Purpose, and Transition in Late Career Interventional Cardiology.

JACC. Cardiovascular interventions·2025
Same author

Functional Coronary Revascularization: A Valuable Underutilized Diagnostic Approach.

Reviews in cardiovascular medicine·2025
Same author

SCAI Expert Consensus Statement on Management of In-Stent Restenosis and Stent Thrombosis.

Journal of the Society for Cardiovascular Angiography & Interventions·2024
Same author

Shared Decision-Making: The More the Patient Knows, the Better the Decision that Is Made.

Reviews in cardiovascular medicine·2024

Related Experiment Video

Updated: Feb 19, 2026

Closed Chest Biventricular Pressure-Volume Loop Recordings with Admittance Catheters in a Porcine Model
07:56

Closed Chest Biventricular Pressure-Volume Loop Recordings with Admittance Catheters in a Porcine Model

Published on: May 18, 2021

4.3K

Damped and Ventricularized Coronary Pressure Waveforms.

Lloyd W Klein1, Divya Korpu

  • 1Advocate Illinois Masonic Medical Center, 836 West Wellington Avenue, Chicago, IL 60657 USA. lloydklein@comcast.net.

The Journal of Invasive Cardiology
|November 1, 2017
PubMed
Summary
This summary is machine-generated.

Ventricularization and damping, commonly used terms in cardiac catheterization, indicate flow limitation. These distinct hemodynamic patterns arise from distorted wave conduction due to catheter- vessel interactions, not synonymous meanings.

More Related Videos

Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts
09:52

Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts

Published on: November 7, 2019

13.8K
Invasive Hemodynamic Assessment for the Right Ventricular System and Hypoxia-Induced Pulmonary Arterial Hypertension in Mice
04:54

Invasive Hemodynamic Assessment for the Right Ventricular System and Hypoxia-Induced Pulmonary Arterial Hypertension in Mice

Published on: October 24, 2019

10.0K

Related Experiment Videos

Last Updated: Feb 19, 2026

Closed Chest Biventricular Pressure-Volume Loop Recordings with Admittance Catheters in a Porcine Model
07:56

Closed Chest Biventricular Pressure-Volume Loop Recordings with Admittance Catheters in a Porcine Model

Published on: May 18, 2021

4.3K
Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts
09:52

Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts

Published on: November 7, 2019

13.8K
Invasive Hemodynamic Assessment for the Right Ventricular System and Hypoxia-Induced Pulmonary Arterial Hypertension in Mice
04:54

Invasive Hemodynamic Assessment for the Right Ventricular System and Hypoxia-Induced Pulmonary Arterial Hypertension in Mice

Published on: October 24, 2019

10.0K

Area of Science:

  • Cardiovascular Physiology
  • Interventional Cardiology
  • Hemodynamics

Background:

  • Ventricularization and damping are frequently observed in cardiac catheterization but their precise hemodynamic origins remain poorly understood.
  • These phenomena are often incorrectly considered synonymous, despite distinct characteristics.
  • Both patterns are attributed to the distortion of normal wave conduction harmonics.

Purpose of the Study:

  • To elucidate the distinct hemodynamic mechanisms underlying ventricularization and damping.
  • To differentiate the specific catheter-vessel interactions that precipitate each waveform pattern.
  • To clarify the clinical significance of recognizing these distinct pressure waveform anomalies.

Main Methods:

  • Analysis of pressure waveforms recorded during cardiac catheterization.
  • Correlation of waveform characteristics with specific catheter positions and vessel anatomy.
  • Distinguishing features of pressure damping (e.g., catheter diameter vs. ostial diameter, catheter against vessel wall) and ventricularization (e.g., catheter in ostial stenosis).

Main Results:

  • Pressure damping is characterized by reduced mean coronary pressure, narrow pulse pressure, and delayed waveform upstroke/downstroke.
  • Ventricularization presents with a diastolic pressure decline, wide pulse pressure, absent dicrotic notch, and presystolic deflection.
  • Ventricularized waveforms exhibit characteristics intermediate between coronary arterial and coronary wedge pressures.

Conclusions:

  • Ventricularization and damping represent distinct hemodynamic events with unique physiological origins.
  • Accurate differentiation is crucial for interpreting potential flow limitations during cardiac catheterization.
  • Understanding these patterns aids in optimizing catheter placement and procedure safety.