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Disease Burden and Variability in Sarcoidosis
Alicia K Gerke1, Marc A Judson2, Yvette C Cozier3
11 Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Iowa, Iowa City, Iowa.
Annals of the American Thoracic Society
|November 1, 2017
Summary
Sarcoidosis significantly impacts health and survival, particularly in African Americans. Addressing disparities and the disease
Area of Science:
- Immunology
- Public Health
- Clinical Medicine
Background:
- Sarcoidosis is a systemic inflammatory disease with significant morbidity and rising mortality.
- Understanding its health care burden and patient outcomes in the U.S. is critical.
Purpose of the Study:
- To review available data on the health care burden and outcomes of sarcoidosis in the United States.
- To identify disparities and factors contributing to poor outcomes.
Main Methods:
- Review of existing data on sarcoidosis health care burden and outcomes in the U.S.
- Analysis of disparities by race, ethnicity, sex, and socioeconomic status.
Main Results:
- African Americans experience disproportionately severe sarcoidosis and higher mortality rates.
- Psychosocial factors (fatigue, depression, cognitive dysfunction) and comorbidities significantly impact outcomes.
- Economic costs to patients and society are substantial but not well-defined.
Conclusions:
- Sarcoidosis outcomes and health care burden are influenced by race, socioeconomic status, and psychosocial factors.
- There is a need for better data collection and monitoring of sarcoidosis impact using technology.
- Improving patient outcomes requires a comprehensive approach addressing medical, psychosocial, and economic aspects.
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