Related Experiment Videos
Decline in cycling of granulocyte-macrophage colony-forming cells with increasing age in mice
C Tejero1, N G Testa, J H Hendry
1Department of Radiobiology, Paterson Institute for Cancer Research, Christie Hospital, Manchester, England.
Experimental Hematology
|January 1, 1989
Abstract:
The cycling state of granulocyte-macrophage progenitor cells (GM-CFC) was measured using the [3H]thymidine suicide technique in individual male B6D2F1 mice. The proportion of the GM-CFC population in S phase was found to decrease from 25%-35% at 1-6 months of age to about 10% in mice greater than 2 years old.