Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Varicose Veins II: Diagnostic Studies and Interprofessional Care01:26

Varicose Veins II: Diagnostic Studies and Interprofessional Care

231
Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
231
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

731
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
731
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

385
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
385
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

338
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
338
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

465
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
465
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

3.3K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative Evaluation of Medial Septal Fat Excision During Infrabrow Blepharoplasty for Medial Upper Eyelid Fullness: A Retrospective Study.

Journal of clinical medicine·2026
Same author

Development of Pentaplex Reverse Transcription Droplet Digital PCR Assay for Simultaneous Detection and Absolute Quantification of HIV-1, HIV-2, HCV, and HBV With Internal Control.

Electrophoresis·2026
Same author

Co-Lifecycle Governance for Learning Medical AI: A Hybrid Convergence Framework for Adaptive Regulatory Oversight.

Journal of medical Internet research·2026
Same author

Unsupervised Acoustic Anomaly Detection for Rotating Machinery Under Submarine-like Environments: Considering Data Scarcity and Background Noise via Proxy Data Generation.

Sensors (Basel, Switzerland)·2026
Same author

Impact of sequenced pharmacological optimisation and multicomponent bundle on early delirium severity trajectories in general medical inpatients.

Age and ageing·2026
Same author

Developmental lineage restriction is driven by loss of genome transcriptional potency.

Cell reports·2026

Related Experiment Video

Updated: Feb 19, 2026

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
10:24

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

Published on: February 12, 2018

10.9K

Surgical Management of Localized Scleroderma.

Jae Hyun Lee1, Soo Yeon Lim1, Jang Hyun Lee2

  • 1Department of Plastic and Reconstructive Surgery, Hanyang University College of Medicine, Seoul, Korea.

Archives of Craniofacial Surgery
|November 2, 2017
PubMed
Summary

Localized scleroderma, a condition causing skin thickening, can lead to facial deformities. Surgical interventions effectively corrected these deformities in six patients, offering a viable treatment option.

Keywords:
DermatosclerosisLinear sclerodermaLocalized sclerodermaMorphea

More Related Videos

Combination of High Ligation and Intraoperative Embolization using Polidocanol for Treatment of Varicoceles
03:06

Combination of High Ligation and Intraoperative Embolization using Polidocanol for Treatment of Varicoceles

Published on: December 22, 2023

996
Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
04:09

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Published on: June 13, 2025

1.2K

Related Experiment Videos

Last Updated: Feb 19, 2026

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
10:24

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

Published on: February 12, 2018

10.9K
Combination of High Ligation and Intraoperative Embolization using Polidocanol for Treatment of Varicoceles
03:06

Combination of High Ligation and Intraoperative Embolization using Polidocanol for Treatment of Varicoceles

Published on: December 22, 2023

996
Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
04:09

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Published on: June 13, 2025

1.2K

Area of Science:

  • Dermatology
  • Plastic Surgery
  • Scleroderma Research

Background:

  • Localized scleroderma involves excessive collagen deposits leading to skin thickening.
  • While not fatal, it impacts quality of life through cosmetic changes and functional limitations.
  • Facial deformities are a rare but significant manifestation of this condition.

Purpose of the Study:

  • To present six cases of localized scleroderma affecting the face.
  • To evaluate the efficacy of surgical management for facial scleroderma.
  • To propose a surgical approach algorithm for localized scleroderma.

Main Methods:

  • Retrospective review of six patients with facial localized scleroderma treated surgically.
  • Surgical interventions included resection with Z-plasty, fat grafting, dermofat grafting, and adipofascial free flaps.
  • Follow-up occurred between April 2003 and February 2015.

Main Results:

  • Successful surgical correction of facial deformities in all six cases.
  • Treated lesions included 'en coup de sabre' (n=4) and oval-shaped facial lesions (n=2).
  • No recurrence of deformities was observed post-surgery.

Conclusions:

  • Surgery is a successful treatment option for localized scleroderma affecting the face.
  • An algorithm for selecting surgical approaches can guide treatment decisions.
  • Further long-term follow-up is warranted, but surgical management should be considered.