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Updated: Feb 19, 2026

Validation of Therapeutic Agent Conjugation to Polyvinyl Alcohol-Coated Medical Devices
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Validation of Therapeutic Agent Conjugation to Polyvinyl Alcohol-Coated Medical Devices

Published on: November 29, 2024

652

A Basic Therapy Gone Awry.

Laura B Galinko1, Steven H Hsu2, Cosmin Gauran1

  • 1Laura B. Galinko is an anesthesiology resident at New York Presbyterian Hospital/Weill Cornell Medical College, New York, New York. At the time of this case report, Steven H. Hsu was a critical care medicine fellow and Michael L. Fingerhood was a pulmonary medicine fellow at Memorial Sloan Kettering Cancer Center, New York, New York. Cosmin Gauran is an assistant attending, Stephen M. Pastores is the critical care fellowship director, and Neil A. Halpern is the director of the Critical Care Center, and Sanjay Chawla is an associate attending in the Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center.

American Journal of Critical Care : an Official Publication, American Association of Critical-Care Nurses
|November 3, 2017
PubMed
Summary
This summary is machine-generated.

Baking soda (sodium bicarbonate) is promoted online as a natural cancer treatment, but this case report details severe metabolic alkalosis from its topical use. This highlights potential dangers of unproven alternative therapies.

Related Experiment Videos

Last Updated: Feb 19, 2026

Validation of Therapeutic Agent Conjugation to Polyvinyl Alcohol-Coated Medical Devices
06:34

Validation of Therapeutic Agent Conjugation to Polyvinyl Alcohol-Coated Medical Devices

Published on: November 29, 2024

652

Area of Science:

  • Oncology
  • Nephrology
  • Toxicology

Background:

  • Baking soda (sodium bicarbonate) is increasingly discussed as an alternative cancer therapy.
  • Proponents suggest alkali therapy neutralizes tumor acidity, inhibiting metastasis.
  • Internet blogs promote it as a safe, natural alternative to chemotherapy with no systemic effects.

Observation:

  • A case study details the first reported instance of severe metabolic alkalosis.
  • This condition resulted from the topical application of sodium bicarbonate for cancer treatment.
  • Such adverse effects from sodium bicarbonate are rare.

Findings:

  • Topical use of baking soda for cancer treatment can lead to severe metabolic alkalosis.
  • This case demonstrates potentially lethal consequences from a common household product.
  • The perceived safety of alternative therapies like alkali therapy may be misleading.

Implications:

  • This case underscores the risks associated with unverified alternative cancer treatments.
  • Healthcare providers should be aware of potential toxicity from seemingly benign substances.
  • Further research is needed to evaluate the safety and efficacy of alternative cancer therapies.