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Synthesis of Functionalized Magnetic Nanoparticles, Their Conjugation with the Siderophore Feroxamine and its Evaluation for Bacteria Detection
Published on: June 16, 2020
Dopamine coated Fe3O4 nanoparticles as enzyme mimics for the sensitive detection of bacteria
Shazia Mumtaz1, Li-Sheng Wang, Syed Zajif Hussain
1Department of Chemistry, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences (LUMS), DHA, Lahore Cantt - 54792, Lahore, Pakistan. ihussain@lums.edu.pk.
Abstract:
We report a simple and economical colorimetric bacterial sensing strategy with catalytic amplification using dopamine-capped iron oxide (Dop-Fe3O4) nanoparticles. These nanoparticles catalyse the oxidation of a chromogenic substrate in the presence of H2O2 into a green colored product. The catalytic activity of the nanoparticles is inhibited in the presence of bacteria, providing naked eye detection of bacteria at 104 cfu mL-1 and by spectrophotometric detection down to 102 cfu mL-1.

