Nodular fasciitis of the orofacial region

The clinical and histologic findings from a study of forty-one cases of nodular fasciitis occurring in the orofacial region are presented. These findings reveal no essential differences in the biologic conduct of nodular fasciitis, whether it occurs in the orofacial area or in its preferred sites, i.e., the extremities and trunk. Various histologic findings are illustrated, none of which, including central necrosis, are indicative of any adverse biologic behavior. Accumulation of a large series of nodular fasciitis of the orofacial region indicates that this anatomic site is perhaps uncommonly but certainly not rarely affected. Pathologists, therefore, need not be so reluctant, as was found in this study, about assigning the diagnosis of nodular fasciitis to orofacial lesions.