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Related Concept Videos

Chronic Pharyngitis01:23

Chronic Pharyngitis

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Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
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Chronic Obstructive Pulmonary Disease-I: Introduction01:20

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Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
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Chronic Obstructive Pulmonary Disease01:24

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COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
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Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

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Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
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Epistaxis01:30

Epistaxis

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Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
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Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
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Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
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Chronic Rhinosinusitis.

Ahmad R Sedaghat1

  • 1Harvard Medical School, Boston, MA, USA.

American Family Physician
|November 3, 2017
PubMed
Summary
This summary is machine-generated.

Chronic rhinosinusitis (CRS) is a paranasal sinus inflammation affecting 1-5% of U.S. adults, significantly impacting quality of life. Diagnosis requires two cardinal symptoms for 12 weeks plus objective evidence, with treatment focusing on improving sinus clearance and drainage.

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Area of Science:

  • Otolaryngology
  • Immunology
  • Pulmonology

Background:

  • Chronic rhinosinusitis (CRS) is a prevalent inflammatory condition of the paranasal sinuses.
  • Affecting 1% to 5% of the U.S. population, CRS significantly diminishes patients' quality of life.
  • Diagnosis requires at least two cardinal symptoms for 12 consecutive weeks, supported by objective evidence.

Purpose of the Study:

  • To outline the diagnostic criteria for chronic rhinosinusitis.
  • To detail current treatment strategies for CRS.
  • To identify patient subgroups that may benefit from specialist referral.

Main Methods:

  • Diagnosis based on cardinal symptoms (facial pain/pressure, hyposmia/anosmia, nasal drainage, nasal obstruction) and objective findings.
  • Objective evidence via physical examination (rhinoscopy, endoscopy) or sinus computed tomography.
  • Treatment evaluation focusing on mucociliary clearance, sinus drainage, infection/inflammation control, and topical medication delivery.

Main Results:

  • First-line treatments include nasal saline irrigation and intranasal corticosteroid sprays.
  • Antibiotics may be indicated for superimposed acute bacterial infections.
  • Endoscopic sinus surgery is an option for refractory cases.

Conclusions:

  • Management of CRS involves enhancing sinus clearance and drainage, alongside addressing infection and inflammation.
  • Referral to an otolaryngologist is recommended for non-responsive cases.
  • Specialist referral to allergists or pulmonologists may be beneficial for patients with specific comorbidities.