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Updated: Feb 19, 2026

Microwave-assisted Intramolecular Dehydrogenative Diels-Alder Reactions for the Synthesis of Functionalized Naphthalenes/Solvatochromic Dyes
Published on: April 1, 2013
Enhancing Intramolecular Chalcogen Interactions in 1-Hydroxy-8-YH-naphthalene Derivatives
Goar Sánchez-Sanz1, Cristina Trujillo2, Ibon Alkorta3
1Irish Centre of High-End Computing & School of Chemistry, University College Dublin , Belfield, Dublin 4, Ireland.
Abstract:
Forty-two peri-substituted naphthalene derivatives presenting chalcogen weak interactions were studied. They correspond to O···Y interactions, Y being O, S, and Se. While the O atom bears H or CH3 substituents (OH and OCH3 groups), the Y atom is substituted by H, F, and CN to explore the effect of these electron-donating and electron-withdrawing substituents on the chalcogen bond strength. The effect of F and CH3 substituents on positions ortho/para (2,4,5,7 of the naphthalene ring) was also studied. Optimizations were performed at the MP2/aug-cc-pVDZ, and binding energies were performed at the MP2/aug-cc-pVDZ followed by an MP2/CBS estimation. The main properties studied were geometries, energies (Eb, Eiso, and Edef), the molecular electrostatic potential, electron density shifts, natural bond order E(2) energies, and the relationship between these properties.
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