Related Experiment Video
Updated: Feb 19, 2026

Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy
Published on: October 24, 2017
Rotational Diffusion of Soft Vesicles Filled by Chiral Active Particles
Jiamin Chen1, Yunfeng Hua1, Yangwei Jiang1
1Department of Physics, Zhejiang University, Hangzhou, 310027, China.
Soft vesicles filled with chiral active particles exhibit unidirectional rotation. Optimal particle angular velocity maximizes vesicle rotation, with diffusion linked to particle dynamics, suggesting applications in nanofabrication and drug delivery.
Area of Science:
- Soft matter physics
- Active matter dynamics
- Biophysics
Background:
- Chiral active particles exhibit self-propulsion and collective behaviors.
- Soft vesicles are model systems for biological cells and microcapsules.
- Understanding particle-vesicle interactions is crucial for micro-device design.
Purpose of the Study:
- To investigate the rotational dynamics of soft vesicles driven by chiral active particles.
- To determine the influence of particle concentration and angular velocity on vesicle motion.
- To explore potential applications in micro-robotics and drug delivery.
Main Methods:
- Overdamped Langevin dynamics simulations were employed.
- Two-dimensional soft vesicles filled with chiral active particles were modeled.
- Vesicle rotation, mean squared displacement, and diffusion coefficients were analyzed.
Main Results:
- Unidirectional rotation of soft vesicles was observed.
- Vesicle rotational velocity depends on particle area fraction and angular velocity, with an optimal angular velocity for maximal rotation.
- Particle concentration affects vesicle curvature continuity; high concentration leads to uniform coverage.
- Vesicle diffusion exhibits oscillations synchronized with particle rotation.
- Vesicle diffusion coefficient decreases monotonically with increasing particle angular velocity.
Conclusions:
- Chiral active particles can induce and control the unidirectional rotation of soft vesicles.
- Vesicle dynamics, including diffusion and rotation, are strongly coupled to the properties of embedded chiral active particles.
- The findings suggest potential applications for chiral active particle-vesicle systems in designing self-rotating micro-devices and targeted drug delivery systems.
More Related Videos
Related Concept Videos
Chirality in Nature
The Movement of Organelles and Vesicles
Pinching-off of Coated Vesicles
Properties of Enantiomers and Optical Activity
Clathrin Coated Vesicles
Chirality
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...

