Comparison between multi-shot gradient echo EPI and balanced SSFP in unenhanced 3T MRA of thoracic aorta in healthy...

The purpose of this study was to compare scan time and image quality between magnetic resonance angiography (MRA) of the thoracic aorta using a multi-shot gradient echo planar imaging (MSG-EPI) and MRA using balanced steady-state free precession (b-SSFP).

Healthy volunteers (n=17) underwent unenhanced thoracic aorta MRA using balanced steady-state free precession (b-SSFP) and MSG-EPI sequences on a 3T MRI. The acquisition time, total scan time, signal-to-noise ratio (SNR) of the thoracic aorta, and the coefficient of variation (CV) of thoracic aorta were compared with paired t-tests. Two radiologists independently recorded the images' contrast, noise, sharpness, artifacts, and overall quality on a 4-point scale.

The acquisition time was 36.2% shorter for MSG-EPI than b-SSFP (115.5±14.4 vs 181.0±14.9s, p<0.01). The total scan time was 40.4% shorter for MSG-EPI than b-SSFP (272±78 vs 456±144s, p<0.01). There was no significant difference in mean SNR between MSG-EPI and b-SSFP scans (17.3±3.6 vs 15.2±4.3, p=0.08). The CV was significantly lower for MSG-EPI than b-SSFP (0.2±0.1 vs. 0.5±0.2, p<0.01). All qualitative scores except for image noise were significantly higher in MSG-EPI than b-SSFP scans (p<0.05).

The MSG-EPI sequence is a promising technique for shortening scan time and yielding more homogenous image quality in MRA of thoracic aorta on 3T scanners compared with the b-SSFP.