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Updated: Feb 19, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Monitoring kidney microanatomy changes during ischemia-reperfusion process using texture analysis of OCT images
Zhifang Li1,2, Qinggong Tang2, Lili Jin2
1College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou, 350007, China.
Abstract:
kidney ischemia-reperfusion (I/R) accounts for the majority of acute kidney injury cases, whose consequences are commonly encountered after kidney transplantation. Optical coherence tomography (OCT) has been applied to image changes in kidney microanatomy and microcirculation. In this paper, we demonstrate a quantitative method for monitoring kidney status during ischemia-reperfusion process using texture properties of OCT images. This approach employs skewness to measure the distribution of en face OCT image intensities at different depths, thus allowing differentiating ischemia-reperfusion status of kidney. The skewness analysis based on quantitative intensity shows promise for monitoring kidney status during ischemia-reperfusion, and the potential for evaluating the viability of transplant kidney.
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