Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

4.9K
The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
4.9K
Cancer Prevention02:59

Cancer Prevention

8.2K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
8.2K
Inhibition of Cdk Activity02:34

Inhibition of Cdk Activity

6.1K
The orderly progression of the cell cycle depends on the activation of Cdk protein by binding to its cyclin partner. However, the cell cycle must be restricted when undergoing abnormal changes. Most cancers correlate to the deregulated cell cycle, and since Cdks are a central component of the cell cycle, Cdk inhibitors are extensively studied to develop anticancer agents. For instance, cyclin D associates with several Cdks, such as Cdk 4/6, to form an active complex. The cyclin D-Cdk4/6 complex...
6.1K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

9.0K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
9.0K
Cancer Therapies02:49

Cancer Therapies

10.2K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
10.2K
Electron Transport Chain: Complex I and II01:46

Electron Transport Chain: Complex I and II

19.1K
The mitochondrial electron transport chain (ETC) is the main energy generation system in the eukaryotic cells. However, mitochondria also produce cytotoxic reactive oxygen species (ROS) due to the large electron flow during oxidative phosphorylation. While Complex I is one of the primary sources of superoxide radicals, ROS production by Complex II is uncommon and may only be observed in cancer cells with mutated complexes.
ROS generation is regulated and maintained at moderate levels necessary...
19.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of clomipramine postnatal exposure on sexual behavior and reproductive organs in female rats: role of sexual experience.

Behavioral and brain functions : BBF·2026
Same author

Genetic variation associated with depression in Latin American populations: a systematic review of single-nucleotide variants.

Frontiers in psychiatry·2026
Same author

Gestational environmental enrichment shapes maternal motivational strategies in postpartum rats.

Behavioural brain research·2026
Same author

Maternal Programming with a Cafeteria Diet Leads to Glucose Intolerance, Increased Insulinemia, Inflammation, and Intestinal Dysbiosis in Rat Offspring.

Preventive nutrition and food science·2026
Same author

Ovarian influence on circadian and infradian modulation of nicotine-seeking in female mice.

Journal of neuroendocrinology·2026
Same author

RAW 264.7 macrophage cell line as a metabolomic model for analyzing and understanding inflammation processes.

Naunyn-Schmiedeberg's archives of pharmacology·2026

Related Experiment Video

Updated: Feb 19, 2026

Author Spotlight: Exploring Seaweed's Bioactive Compounds for Sustainable Innovations in Industries
10:18

Author Spotlight: Exploring Seaweed's Bioactive Compounds for Sustainable Innovations in Industries

Published on: November 21, 2023

3.6K

Anticancer activity of seaweeds.

Anllely G Gutiérrez-Rodríguez1, Claudia Juárez-Portilla2, Tatiana Olivares-Bañuelos3

  • 1Centro de Investigaciones Biomédicas, Universidad Veracruzana, Avenue Dr Luis Castelazo Ayala s/n, Col. Industrial Ánimas, 91190 Xalapa, Veracruz, Mexico; Programa de Doctorado en Ciencias Biomédicas, Universidad Veracruzana, Avenue Dr Luis Castelazo Ayala s/n, Col. Industrial Ánimas, 91190 Xalapa, Veracruz, Mexico.

Drug Discovery Today
|November 7, 2017
PubMed
Summary

Marine algae offer promising natural compounds with anticancer activity. This review explores seaweed-derived molecules and their potential in cancer treatment, highlighting their biological activities in various models.

More Related Videos

Author Spotlight: Exploring Salidroside's Molecular Mechanisms in Breast Cancer Treatment
11:13

Author Spotlight: Exploring Salidroside's Molecular Mechanisms in Breast Cancer Treatment

Published on: June 9, 2023

2.4K
Establishment of Hepatocarcinoma in BALB/c-nu Mice and Investigation of the Therapeutic Effect of the Sanleng Jiashen Formula
09:03

Establishment of Hepatocarcinoma in BALB/c-nu Mice and Investigation of the Therapeutic Effect of the Sanleng Jiashen Formula

Published on: January 26, 2024

734

Related Experiment Videos

Last Updated: Feb 19, 2026

Author Spotlight: Exploring Seaweed's Bioactive Compounds for Sustainable Innovations in Industries
10:18

Author Spotlight: Exploring Seaweed's Bioactive Compounds for Sustainable Innovations in Industries

Published on: November 21, 2023

3.6K
Author Spotlight: Exploring Salidroside's Molecular Mechanisms in Breast Cancer Treatment
11:13

Author Spotlight: Exploring Salidroside's Molecular Mechanisms in Breast Cancer Treatment

Published on: June 9, 2023

2.4K
Establishment of Hepatocarcinoma in BALB/c-nu Mice and Investigation of the Therapeutic Effect of the Sanleng Jiashen Formula
09:03

Establishment of Hepatocarcinoma in BALB/c-nu Mice and Investigation of the Therapeutic Effect of the Sanleng Jiashen Formula

Published on: January 26, 2024

734

Area of Science:

  • Marine Biology
  • Pharmacology
  • Biochemistry

Background:

  • Cancer remains a significant global health challenge with unmet treatment needs.
  • Natural products, particularly from marine sources, are explored as alternative therapeutic strategies.
  • Marine algae possess rich biodiversity and yield diverse functional compounds like terpenes, polyphenols, and polysaccharides.

Purpose of the Study:

  • To review the current understanding of anticancer activities derived from marine algae.
  • To highlight the potential of seaweed-derived compounds in cancer therapy.
  • To discuss the biological activities and targeted molecules of these marine compounds.

Main Methods:

  • Literature review of scientific studies on marine algae and their anticancer properties.
  • Analysis of in vitro and in vivo models demonstrating seaweed-derived compound efficacy.
  • Examination of the chemical structures and biological activities of marine algae compounds.

Main Results:

  • Marine algae contain numerous compounds, including terpenes, polyphenols, phlorotannins, and polysaccharides.
  • These compounds exhibit significant anticancer activity in both in vitro and in vivo experimental models.
  • Seaweed-derived molecules demonstrate the ability to target key molecules involved in cancer progression.

Conclusions:

  • Marine algae represent a valuable source of natural compounds with demonstrated anticancer potential.
  • Further research into seaweed-derived compounds could lead to novel cancer treatment strategies.
  • The complex structures of these marine compounds offer diverse therapeutic applications in oncology.