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Surface modification of biomaterials and biomedical devices using additive manufacturing
Susmita Bose1, Samuel Ford Robertson1, Amit Bandyopadhyay1
1W. M. Keck Biomedical Materials Research Lab, School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164, United States.
Acta Biomaterialia
|November 8, 2017
Summary
Additive manufacturing (AM) enhances biomaterials by precisely modifying surfaces for improved medical device performance. This technology offers tailored solutions for tissue replacement and patient-matched implants, boosting in vitro and in vivo outcomes.
Area of Science:
- Biomaterials Engineering
- Medical Device Technology
- Surface Science
Background:
- Growing demand for synthetic biomaterials in medical devices, pharmaceuticals, and tissue replacement, driven by an aging global population.
- Increasing use of patient-matched devices due to technological advancements and integration.
- Significant rise in additive manufacturing (AM), also known as 3D printing (3DP), applications for Class I, II, and III medical devices.
Purpose of the Study:
- To review the application of AM in surface-modified biomaterials for enhanced performance.
- To explore how AM enables spatial control in surface modification during a single manufacturing process.
- To discuss the future outlook of AM in biomaterial surface modification.
Main Methods:
- Review of current literature on additive manufacturing techniques for biomaterial surface modification.
- Analysis of AM's role in tailoring surface properties for improved material-tissue interactions.
- Examination of AM's potential for creating next-generation medical devices.
Main Results:
- AM allows for deliberate and spatially specific modification of biomaterial surfaces.
- Surface modification via AM can significantly enhance both in vitro and in vivo performance of biomaterials.
- AM offers a unique approach to engineer both bulk and surface properties of biomaterials.
Conclusions:
- Additive manufacturing is a powerful tool for advancing biomaterial surface modification.
- AM-enabled surface engineering is crucial for improving the success of implanted medical devices.
- The future of biomaterial development for medical applications will likely involve increased use of AM for tailored surface properties.

