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Diffusion-weighted imaging in hemorrhagic abdominal and pelvic lesions: restricted diffusion can mimic malignancy
Chandana Lall1, Vlad Bura2, Thomas K Lee3
1Department of Radiological Sciences, University of California, Irvine, 101 The City Dr South, Suite 0115, Orange, CA, 92868, USA.
Abstract:
Diffusion-weighted imaging (DWI) is an increasingly utilized sequence in the assessment of abdominal and pelvic lesions. Benign lesions containing hemorrhagic products, with conglomerates of tightly packed blood cells or fibers, can have restricted water diffusion on DWI and apparent diffusion coefficient maps. Such lesions can have restricted diffusion erroneously attributed to malignancy. This review illustrates benign hemorrhagic lesions displaying restricted diffusion, with histopathologic correlation in relevant cases.
Insights
Benign hemorrhagic lesions in the abdomen and pelvis can mimic malignancy on diffusion-weighted imaging (DWI). This review highlights these lesions to prevent misdiagnosis of cancer, emphasizing DWI
Area of Science:
- Radiology
- Medical Imaging
- Pathology
Background:
- Diffusion-weighted imaging (DWI) is crucial for evaluating abdominal and pelvic lesions.
- Restricted diffusion on DWI can be misinterpreted as malignancy.
- Hemorrhagic lesions pose a diagnostic challenge.
Purpose of the Study:
- To review benign hemorrhagic lesions that exhibit restricted diffusion on DWI.
- To differentiate these lesions from malignant ones.
- To provide histopathologic correlation for accurate diagnosis.
Main Methods:
- Literature review of DWI findings in abdominal and pelvic lesions.
- Analysis of cases with benign hemorrhagic lesions showing restricted diffusion.
- Correlation with histopathologic findings.
Main Results:
- Benign hemorrhagic lesions can demonstrate restricted water diffusion.
- This restricted diffusion can be erroneously attributed to malignancy.
- Histopathologic correlation confirms the benign nature of these lesions.
Conclusions:
- Awareness of benign hemorrhagic lesions with restricted diffusion is essential.
- DWI interpretation requires careful consideration of lesion characteristics.
- Accurate diagnosis prevents unnecessary treatment for benign conditions.
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