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Updated: Feb 19, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
Flavonol glycosides from the fruits of Evodia rutaecarpa
Shan-Shan Liu1,2, Yun-Tao Dai1, Feng Sui1
1a Institute of Chinese Materia Medica , China Academy of Chinese Medical Sciences , Beijing 100700 , China.
Abstract:
Two new flavonol glycosides, limocitrin 3-O-β-D-xylopyranosyl(1→2)-β-D-glucopyranoside (1) and limocitrin 3-O[2-O-β-D-xylopyranosyl-6-O-α-L-rhamnopyranosyl]-β-D-glucopyranoside (2), together with eight known analogs (3-10), were isolated from the fruits of Evodia rutaecarpa. Their structures were elucidated on the basis of spectroscopic analyses and chemical evidences. Meanwhile, Nrf2 inducing abilities of seven isolated compounds were evaluated, and compounds 1, 2, 6, 7, and 8 exhibited moderate effect on Nrf2.
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