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Ocular and periocular hemangiosarcoma in six horses
Nicole M Scherrer1, Mary Lassaline2, Julie Engiles1,3
1Department of Clinical Studies, New Bolton Center, University of Pennsylvania School of Veterinary Medicine, 382 West Street Road, Kennett Square, PA, 19348, USA.
Veterinary Ophthalmology
|November 8, 2017
Summary
Complete surgical excision may resolve ocular and periocular hemangiosarcoma in horses. Ultraviolet light exposure may contribute to the development of these equine tumors.
Area of Science:
- Veterinary Oncology
- Equine Pathology
- Ophthalmology
Background:
- Hemangiosarcoma is a vascular tumor that can affect horses.
- Ocular and periocular involvement presents unique diagnostic and therapeutic challenges.
Purpose of the Study:
- To characterize ocular and periocular hemangiosarcoma in horses.
- To determine the prognosis and potential risk factors for these tumors.
Main Methods:
- Retrospective review of medical records (2007-2015) for six horses with histologically confirmed ocular or periocular hemangiosarcoma.
- Analysis of signalment, clinical signs, tumor characteristics, treatments, and outcomes.
- Histopathological review by a board-certified pathologist.
Main Results:
- No specific breed, age, or sex predilection was identified.
- Common tumor sites included the temporal limbus, third eyelid, and uvea.
- Five of six horses had lightly pigmented periocular haircoats and solar elastosis, suggesting ultraviolet light damage.
- Complete surgical excision was associated with no recurrence in 4/6 horses; topical mitomycin C further reduced recurrence.
- Incomplete excision was linked to postexcisional recurrence.
Conclusions:
- Complete surgical excision appears to be an effective treatment for equine ocular and periocular hemangiosarcoma.
- Ultraviolet light exposure is a potential contributing factor to the development of these tumors in horses.
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