Related Experiment Video
Updated: Feb 19, 2026

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
Published on: August 16, 2021
Heartmate III Replacement for Recurring Left Ventricular Assist Device Pump Thrombosis
Yaron D Barac1, Jacob N Schroder1, Mani A Daneshmand1
1From the Division of Cardiothoracic Surgery, Duke University Medical Center, Durham, NC.
Patients needing multiple heart pump replacements due to device failure can now benefit from the Heartmate III Left Ventricular Assist Device (LVAD). This advanced LVAD shows promise in reducing pump thrombosis events in heart failure patients.
Area of Science:
- Cardiology
- Biomedical Engineering
- Medical Device Technology
Background:
- Advanced systolic heart failure necessitates mechanical circulatory support.
- Left Ventricular Assist Devices (LVADs) are crucial for end-stage heart failure management.
- Pump thrombosis is a significant complication leading to LVAD replacement.
Observation:
- The Heartmate III LVAD demonstrates a notably low incidence of pump thrombosis.
- This study examines cases involving multiple pump thrombosis events.
- Successful replacement with the Heartmate III LVAD was achieved in these complex cases.
Findings:
- The Heartmate III LVAD offers a viable solution for patients experiencing recurrent pump thrombosis.
- Successful outcomes were reported for patients requiring multiple LVAD interventions.
- This device may mitigate the risk associated with repeated LVAD surgeries.
Implications:
- The Heartmate III LVAD could improve long-term outcomes for heart failure patients prone to device thrombosis.
- This technology offers a potential reduction in rehospitalization and morbidity.
- Further research into the durability and long-term performance of the Heartmate III is warranted.
Related Concept Videos
Cardiomyopathy V: Interprofessional Care
Heart Failure VI: Adjunct Therapies
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Cardiac Catheterization III: Left Heart Catheterization
Mitral Stenosis III: Medical Management
Cardiomyopathy II: Dilated Cardiomyopathy

