Related Experiment Video
Updated: Feb 19, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
A Review of Best Practices for Intravenous Push Medication Administration
Janelle R Lenz1, Daniel D Degnan, John B Hertig
1Eli Lilly and Company (Dr Lenz), Purdue University College of Pharmacy (Drs Degnan and Hertig), University of Michigan College of Pharmacy (Dr Stevenson), and Visante, Inc (Dr Stevenson). Janelle R. Lenz, PharmD, is internal liaison at Eli Lilly and Company, supporting field-based medical liaisons within the areas of neurodegeneration and pain. At the time of writing this article, Dr Lenz was completing a medication safety fellowship with the Purdue College of Pharmacy and Lilly. Daniel D. Degnan, PharmD, MS, CPPS, FASHP, is the senior project manager at the Center for Medication Safety Advancement at Purdue University College of Pharmacy. Previously, he spent 10 years as the medication safety officer at a large health system in Indiana. John B. Hertig, PharmD, MS, CPPS, is the associate director at the Center for Medication Safety Advancement at the Purdue University College of Pharmacy. He has professional interests in pharmacy practice health policy. He currently serves as a contributing editor for several quality and safety publications. James G. Stevenson, PharmD, FASHP, is a professor in the department of clinical pharmacy at the University of Michigan College of Pharmacy. He is also president of Visante, Inc, a medicines management consulting company. He served as chief pharmacy officer for the University of Michigan Health System for 15 years.
Abstract:
In 2015, the Institute for Safe Medication Practices (ISMP) released safe practice guidelines for adult intravenous (IV) push medications. ISMP's most recent set of guidelines has added to a growing list of recommendations from professional groups on the safe use of IV medications. These recommendations and guidelines vary with regard to their audience, scope, and terminology. In some ways, these variations may contribute to confusion and delayed adoption of the standards. This report attempts to provide clarity about the rationale and background regarding the need for practice improvement, discussion of various guidelines, and practice mitigation strategies to improve patient safety.
Related Concept Videos
Routes of Drug Administration: Parenteral
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices
One-Compartment Open Model for IV Bolus Administration: General Considerations
The drug's presence in the body is defined by an equation representing the difference between the rates of drug entry and exit. Key parameters—elimination rate constant,...
IV Infusion to Oral Dosing: Conversion Methods
Drug Delivery: Parenteral Route
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
Drug Accumulation During Multiple Dosing: Repetitive IV Injections

