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The Role of Immunoglobulin in the Treatment of Immune-Mediated Peripheral Neuropathies

Alejandro Tobon1

  • 1University of Texas Health Science Center, San Antonio, Texas.

Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society
|November 8, 2017
PubMed

Immune-mediated neuropathies are a group of peripheral nerve disorders characterized by motor or sensory deficits caused by inflammation leading to demyelination or axonal injury. Intravenous immunoglobulin (IVIg) has been demonstrated to be an effective therapy for the 3 most common immune-mediated neuropathies: Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, and multifocal motor neuropathy. This review summarizes current data on the rationale for the use of IVIg in immune-mediated neuropathies, addressing mechanism of action, clinical evidence, and practical considerations for its use.

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