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Introduction to Metabolism01:30

Introduction to Metabolism

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Metabolism encompasses all biochemical reactions in a living organism, facilitating both the breakdown and synthesis of biomolecules. These metabolic processes are categorized into catabolic and anabolic pathways, which operate in a coordinated manner to ensure energy balance and cellular function.Catabolic Pathways and Energy ReleaseCatabolic pathways involve the breakdown of complex macromolecules such as carbohydrates, lipids, and proteins into smaller structures like monosaccharides, fatty...
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Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
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Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
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The pentose phosphate pathway (PPP) operates in parallel with glycolysis, facilitating the metabolism of both pentoses and glucose. This pathway consists of two distinct phases: the oxidative and non-oxidative phases. While it does not directly generate ATP, the intermediates formed during the process can integrate into glycolysis, contributing to cellular energy metabolism when required.Oxidative Phase: NADPH ProductionThe oxidative phase of the pentose phosphate pathway is primarily...
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Updated: Feb 19, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways
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TabPath: interactive tables for metabolic pathway analysis.

Lauro Ângelo Gonçalves de Moraes1,2, Érica Barbosa Felestrino3, Renata de Almeida Barbosa Assis3

  • 1Laboratório Multiusuário de Bioinformática, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG 35400-000, Brazil.

Bioinformatics (Oxford, England)
|November 8, 2017
PubMed
Summary
This summary is machine-generated.

TabPath is a new web tool that simplifies comparing metabolic pathways across different genomes. It helps researchers understand how genome differences affect organism phenotypes by generating easy-to-read tables.

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Area of Science:

  • Comparative genomics
  • Metabolic pathway analysis
  • Bioinformatics tools

Background:

  • Understanding genome-based phenotypic differences across organisms relies on comparative metabolic pathway information.
  • Existing platforms offer extensive metabolic data but lack user-friendly comparative analysis features.

Purpose of the Study:

  • To introduce TabPath, a web-based tool designed to facilitate the comparison of metabolic pathways across multiple genomes.
  • To enable researchers to analyze variations in metabolism among selected organisms through user-friendly tables.

Main Methods:

  • TabPath utilizes data from the Kyoto Encyclopedia of Genes and Genomes (KEGG).
  • Users can select specific pathways and genomes of interest.
  • The tool generates comparative tables for metabolic pathway analysis.

Main Results:

  • TabPath provides a streamlined approach to comparing metabolic pathways.
  • The generated tables highlight variations in metabolism among selected organisms.
  • The tool enhances the understanding of genome-based phenotypic differences.

Conclusions:

  • TabPath offers a valuable resource for comparative metabolic pathway analysis.
  • The tool simplifies the interpretation of metabolic variations across genomes.
  • It supports research into genome-based phenotypic diversity.